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Microbiology Independent Research Journal (MIR Journal)

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Two years of experience in hospital surveillance for the severe influenza like illnesses in St. Petersburg: etiology, clinical characterization of diseases, antigenic and genetic properties of isolated influenza viruses

https://doi.org/10.18527/2500-2236-2015-2-1-44-55

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Аннотация

In this paper, we analyze the etiology of the diseases occurring during two consecutive influenza epidemic seasons in St. Petersburg, Russian Federation. The analysis is based on the results of the PCR diagnostics of the clinical samples collected from patients hospitalized in three St. Petersburg hospitals with influenza like illnesses (ILI). It was shown that the influenza virus A(H1N1)pdm09 was the dominant causative agent during the 2012-2013 epidemic season while, in the 2013-2014 season, A(H3N2) virus was predominant among adults and children. The influenza B virus activity was high in the 2012-2013 season and low in the 2013-2014 season. During both seasons, the main causative agent for the hospitalization of young children was respiratory syncytial virus (RSV), followed by rhinovirus and influenza virus. The rate of involvement of parainfluenza, adenovirus, metapneumovirus and coronavirus was low and was negligible for bocavirus. Children 0-2 and 3-6 years old formed the group of patients that was affected by acute respiratory infection agents the most. Children younger than 3 months old were the major group of the intensive care unit (ICUs) patients and only 27.5% of them were adults. RSV and rhinovirus were the leading cause of ILI among the children admitted to ICU. Among the adult patients admitted to the ICU, only influenza A(H1N1)pdm09, A(H3N2) and B viruses were detected during both influenza seasons.
According to the results of the antigenic and genetic analysis, most influenza A(H1N1)pdm09 and A(H3N2) viruses circulating in St. Petersburg matched the vaccine strains recommended by the WHO for vaccine composition in the 2012-2013 and 2013-2014 seasons.

Ключевые слова


Об авторах

A. A. Sominina
Research Institute of Influenza
Россия

Anna Sominina

Saint Petersburg



M. M. Pisareva
Research Institute of Influenza
Россия
Saint Petersburg


M. P. Grudinin
Research Institute of Influenza
Россия
Saint Petersburg


M. Yu. Eropkin
Research Institute of Influenza
Россия
Saint Petersburg


N. I. Konovalova
Research Institute of Influenza
Россия
Saint Petersburg


V. F. Sukhovetskaya
Research Institute of Influenza
Россия
Saint Petersburg


O. I. Afanasieva
Research Institute of Influenza
Россия
Saint Petersburg


L. V. Voloshuk
Research Institute of Influenza
Россия
Saint Petersburg


A. B. Komissarov
Research Institute of Influenza
Россия
Saint Petersburg


Zh. V. Buzitskaya
Research Institute of Influenza
Россия
Saint Petersburg


A. V. Fadeev
Research Institute of Influenza
Россия
Saint Petersburg


K. A. Stolyarov
Research Institute of Influenza
Россия
Saint Petersburg


E. A. Smorodintseva
Research Institute of Influenza
Россия
Saint Petersburg


V. S. Afanasieva
Research Institute of Influenza
Россия
Saint Petersburg


M. A. Yanina
Research Institute of Influenza
Россия
Saint Petersburg


V. V. Gonchar
Research Institute of Influenza
Россия
Saint Petersburg


L. V. Osidak
Research Institute of Influenza
Россия
Saint Petersburg


A. A. Go
Research Institute of Influenza
Россия
Saint Petersburg


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Для цитирования:


Sominina A.A., Pisareva M.M., Grudinin M.P., Eropkin M.Y., Konovalova N.I., Sukhovetskaya V.F., Afanasieva O.I., Voloshuk L.V., Komissarov A.B., Buzitskaya Z.V., Fadeev A.V., Stolyarov K.A., Smorodintseva E.A., Afanasieva V.S., Yanina M.A., Gonchar V.V., Osidak L.V., Go A.A. Two years of experience in hospital surveillance for the severe influenza like illnesses in St. Petersburg: etiology, clinical characterization of diseases, antigenic and genetic properties of isolated influenza viruses. Microbiology Independent Research Journal (MIR Journal). 2015;2(1):44-55. https://doi.org/10.18527/2500-2236-2015-2-1-44-55

For citation:


., ., ., ., ., ., ., ., ., ., ., ., ., ., ., ., ., . Two years of experience in hospital surveillance for the severe influenza like illnesses in St. Petersburg: etiology, clinical characterization of diseases, antigenic and genetic properties of isolated influenza viruses. Microbiology Independent Research Journal (MIR Journal). 2015;2(1):44-55. https://doi.org/10.18527/2500-2236-2015-2-1-44-55

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ISSN 2500-2236 (Online)