ISSN 2500-2236
DOI-prefix: 10.18527/2500-2236

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Volume 5, Number 1, 2018
... losses in the poultry industry. The development of an effective and safe vaccine for the broad protection of poultry from H5N1 HPAIVs remains an important goal. Prevention of the virus transmission ...
Authors: Elizaveta Boravleva, Alexandra Gambaryan
Volume 3, Number 1, 2016
... The biological basis for the restricted immunogenicity of some live attenuated influenza vaccine strains generated on the backbone of the cold adapted (ca) A/Singapore/1/1957/ca (H2N2) influenza A ...
Authors: Andrea Wolkerstorfer, Dietmar Katinger, Julia Romanova
Volume 4, Number 1, 2017
... In order to decrease the morbidity and mortality caused by seasonal influenza outbreaks, several hundred million vaccine doses are produced worldwide each year. The predominant substrate for the ...
Authors: Julia Romanova
Volume 3, Number 1, 2016
... need for a more effective universal influenza vaccine that provides a long-lasting broad cross-protective immunity, and is able to protect against influenza A and B viruses of all known subtypes. The basic approaches to as well as challenges of creating such a vaccine are discussed in this review. ...
Authors: Andrej Y. Egorov
Volume 1, number 1, 2014
... . Additionally, a number of reassortants were generated containing HA and NA genes from VN1203, HK156, IND05, ANH01, tkTK01 viruses in combination with other genes from the IVR-116 vaccine strain. Virus ...
Authors: Mariia Sergeeva, Artem Krokhin, Mikhail Matrosovich, Tatyana Matrosovich, Markus Wolschek, Oleg Kiselev, Julia Romanova
Volume 3, Number 1, 2016
... important information, concerning the development of a new live modified cold-adapted (ca) equine influenza virus vaccine based on the A/HK/Otar/6:2/2010 strain is summarized. We discuss a number of ...
Authors: Kaissar Tabynov
Volume 3, Number 1, 2016
... post immunization. The obtained sera (7 animals per group) were treated with the neuraminidase inhibitor (Denka-Seiken, Japan) and tested for the presence of antibodies to the vaccine virus Len17/H6 in ...
Authors: Yulia A. Desheva, Tatiana A. Smolonogina, Galina O. Landgraf, Larisa G. Rudenko
Том 3, номер 1, 2016
... important information, concerning the development of a new live modified cold-adapted equine influenza virus vaccine based on the A/HK/Otar/6:2/2010 strain is summarized. We discuss a number of unique ...
Authors: К. К. Табынов
Том 1, номер 1, 2014
... change (pH of fusion or activation) of avian highly pathogenic influenza viruses resulted in the low stability of native HA conformation and affected the vaccine quality. The 58Lys→Ile mutation ...
Authors: М.В. Сергеева, А. Крохин, М. Матросович, Т. Матросович, М. Волшек, О.И. Киселев, Ю.Р. Романова
Том 5, номер 1, 2018
... losses in the poultry industry. The development of an effective and safe vaccine for the broad protection of poultry from H5N1 HPAIVs remains an important goal. Prevention of the virus transmission ...
Authors: Е. Ю. Боравлева, А. С. Гамбарян
Volume 2, Number 1, 2015
... divided into two antigenically separate groups: a group that differed from both the old (A/New Caledonia/20/1999) and the new (A/Solomon Islands/3/2006) vaccine strains and the group which was very ...
Authors: Mikhail P. Grudinin, Maria M. Pisareva, Andrey B. Komissarov, Anna A. Kosheleva, Zhanna V. Buzitskaya, Marina A. Stukova, Alexandra V. Prokopetz, Daria M. Danilenko, Nadezhda I. Konovalova, Tamara G. Lobova, Anna A. Sominina, Oleg I. Kiselev
Том 4, номер 1, 2017
... In order to decrease the morbidity and mortality caused by seasonal influenza outbreaks, several hundred million vaccine doses are produced worldwide each year. The predominant substrate for the ...
Authors: Ю.Р. Романова
Том 3, номер 1, 2016
... /herring gull/Sarma/2006/887 (H6N1) is temperature sensitive (ts) and cold-adapted (ca) in chicken embryos and attenuated in mice when administered intranasally. This reassortant can be recommended as a live influenza vaccine candidate for humans. ...
Authors: Ю. А. Дешева, T. А. Смолоногина, Г. О. Ландграф, Л. Г. Руденко
Volume 2, Number 1, 2015
... matched the vaccine strains recommended by the WHO for vaccine composition in the 2012-2013 and 2013-2014 seasons.  ...
Authors: Anna A. Sominina, Maria M. Pisareva, Mikhail P. Grudinin, Mikhail Yu. Eropkin, Nadezhda I. Konovalova, Vera F. Sukhovetskaya, Olga I. Afanasieva, Lubov V. Voloshuk, Andrey B. Komissarov, Zhanna V. Buzitskaya, Artem V. Fadeev, Kirill A. Stolyarov, Elizaveta A. Smorodintseva, Veronika S. Afanasieva, Marina A. Yanina, Vitalii V. Gonchar, Ludmila V. Osidak, Alexey A. Go
Том 3, номер 1, 2016
... another subtype. In this regard, there is an urgent need for a more effective universal influenza vaccine that provides a long-lasting wide cross-protective immunity, and is able to resist to influenza A ...
Authors: А.Ю. Егоров
Volume 5, Number 1, 2018
... [8], and macaques [9]. A live intranasal influenza vaccine, which was developed on the basis of the influenza virus with the ...
Authors: Kirill A. Vasilyev, Maria A. Yukhneva, Anna-Polina S. Shurygina, Marina A. Stukova, Andrej Y. Egorov
Volume 4, Number 1, 2017
... influenza vaccine is the reassortment of the epidemic virus with the cold adapted donor of attenuation. Reassortment is achieved by the simultaneous infection of CE with two parental strains and ...
Authors: Rustam N. Heydarov, Natalia F. Lomakina, Elizaveta Yu. Boravleva, Ivan S. Kholodilov, Alexandra S. Gambaryan, Vladimir M. Mikhailovich, Eugene E. Fesenko
Volume 5, Number 1, 2018
... present, there are numerous pieces of evidence that antiviral vaccination may reduce the risk of bacterial complications post ARVI. It was shown that immunization with an inactivated influenza vaccine ...
Authors: Andrej Egorov
Volume 2, Number 1, 2015
... population. It is also evident that in the process of anti-influenza vaccine development it is necessary to consider the possibility of the vaccine’s “genetic” orientation ...
Authors: O. I. Kiselev, A. B. Komissarov, O.S.Konshina, M.N.Dmitrieva, E.G.Deyeva, T.V.Sologub, V.I.Pokrovskiy