ISSN 2500-2236
DOI-prefix: 10.18527/2500-2236

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Volume 1, number 1, 2014
... Conventional inactivated vaccines made from these viruses were shown to have decreased HA content and immunogenicity compared to seasonal preparations. ...
Authors: Mariia Sergeeva, Artem Krokhin, Mikhail Matrosovich, Tatyana Matrosovich, Markus Wolschek, Oleg Kiselev, Julia Romanova
Volume 3, Number 1, 2016
... Another factor compromising the immunogenicity of a vaccine candidate is the incompatibility of epidemic virus HA with the M gene of the master strain. ...
Authors: Andrea Wolkerstorfer, Dietmar Katinger, Julia Romanova
Volume 5, Number 1, 2018
... However, the innate immune mechanisms that cause the increased immunogenicity of influenza viruses with altered NS1 proteins are poorly understood. ...
Authors: Kirill A. Vasilyev, Maria A. Yukhneva, Anna-Polina S. Shurygina, Marina A. Stukova, Andrej Y. Egorov
Volume 4, Number 1, 2017
... These vaccine candidates showed the decreased immunogenicity upon the intranasal immunization of ferrets. ...
Authors: Julia Romanova
Том 1, номер 1, 2014
... Conventional inactivated vaccines made from these viruses were shown to have decreased HA content and immunogenicity compared to seasonal preparations. ...
Authors: М.В. Сергеева, А. Крохин, М. Матросович, Т. Матросович, М. Волшек, О.И. Киселев, Ю.Р. Романова
Volume 3, Number 1, 2016
... At the same time, the main disadvantages of inactivated vaccines are weak immunogenicity caused by the formation of an exclusively humoral immune response as well as short-term immunity, which requires ...
Authors: Kaissar Tabynov
Том 5, номер 1, 2018
... However, the innate immune mechanisms that cause the increased immunogenicity of influenza viruses with altered NS1 proteins are poorly understood. ...
Authors: К. А. Васильев, М. А. Юхнева, А.-П. С. Шурыгина, М. А. Стукова, А. Ю. Егоров
Volume 3, Number 1, 2016
... It should be mentioned that the vaccine candidate Len17/H6 demonstrated the highest immunogenicity in mice after the single immunization compared to other vaccine candidates obtained with the apathogenic ...
Authors: Yulia A. Desheva, Tatiana A. Smolonogina, Galina O. Landgraf, Larisa G. Rudenko
Volume 4, Number 1, 2017
... Pathogenicity and immunogenicity for the mice of avian influenza viruses that differ in amino acids at position 66 of the PB1-F2 protein. ...
Authors: Rustam N. Heydarov, Natalia F. Lomakina, Elizaveta Yu. Boravleva, Ivan S. Kholodilov, Alexandra S. Gambaryan, Vladimir M. Mikhailovich, Eugene E. Fesenko
Volume 5, Number 1, 2018
... apathogenic wild duck influenza virus А/duck/Moscow/4182/2010 (H5N3, named dk/4182) and attenuated experimental reassortants made on the base of different donors was conducted in order to compare their safety, immunogenicity ...
Authors: Elizaveta Boravleva, Alexandra Gambaryan
Volume 3, Number 1, 2016
... In contrast, the stem of the HA that is located in close proximity to the viral membrane is highly conservative and characterized by low immunogenicity [11]. ...
Authors: Andrej Y. Egorov