ISSN 2500-2236
DOI-prefix: 10.18527/2500-2236

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Volume 5, Number 1, 2018
... were performed at 8 and 21 days post immunization (d.p.i.) to analyze the adaptive immune response. Cell stimulation was performed in flat-bottomed 96-well plates (Nunc, Denmark) for 6 h ...
Authors: Kirill A. Vasilyev, Maria A. Yukhneva, Anna-Polina S. Shurygina, Marina A. Stukova, Andrej Y. Egorov
Volume 5, Number 1, 2018
... occurrence of severe bacterial complications is also affected by the chronic diseases that have an impact on the regulation of the innate immune response. This review summarizes the current concept ...
Authors: Andrej Egorov
Том 5, номер 1, 2018
... virus replication in the intestinal epithelial cells that cause a well-balanced and broad immune response providing protection against the viruses of distant clades. The broad protection is the important ...
Authors: Е. Ю. Боравлева, А. С. Гамбарян
Volume 3, Number 1, 2016
... immunization. The antibody titers were measured by HAI assay and ELISA [17]. For the HAI assay, immune serum samples were treated with a receptor-destroying enzyme (Denka ...
Authors: Andrea Wolkerstorfer, Dietmar Katinger, Julia Romanova
Том 5, номер 1, 2018
... . Occurrence of severe bacterial complications is also affected by the chronic diseases that have an impact on the regulation of the innate immune response. This review summarizes the current conception of the ...
Authors: А. Ю. Егоров
Том 5, номер 1, 2018
... cells upon immunization with А/PR8/NS124 lead to a more effective presentation of viral antigens and, therefore, promote an increased antigen-specific CD8+ immune response. ...
Authors: К. А. Васильев, М. А. Юхнева, А.-П. С. Шурыгина, М. А. Стукова, А. Ю. Егоров
Volume 5, Number 1, 2018
... virus replication in the intestinal epithelial cells that cause a well-balanced and broad immune response providing protection against the viruses of distant clades. The broad protection is the important ...
Authors: Elizaveta Boravleva, Alexandra Gambaryan
Volume 3, Number 1, 2016
... protective role of antibodies against the conservative influenza virus antigens The main humoral immune response during the influenza infection is directed against the HA surface glycoprotein ...
Authors: Andrej Y. Egorov
Volume 3, Number 1, 2016
... is significantly lower. Moreover, the virus Len17/H6 caused the systemic immune response in mice three weeks post the single immunization with the antibody geometric mean titer (GMT) of 17.4. It should ...
Authors: Yulia A. Desheva, Tatiana A. Smolonogina, Galina O. Landgraf, Larisa G. Rudenko
Volume 2, Number 1, 2015
... The system of genetic control of innate immune responses to influenza infection and gene function allows for the development of systemic treatment of influenza with a focus on the phenotype of ...
Authors: O. I. Kiselev, A. B. Komissarov, O.S.Konshina, M.N.Dmitrieva, E.G.Deyeva, T.V.Sologub, V.I.Pokrovskiy
Volume 3, Number 1, 2016
... [2]. At the same time, the main disadvantages of inactivated vaccines are weak immunogenicity caused by the formation of an exclusively humoral immune response as well as ...
Authors: Kaissar Tabynov
Volume 4, Number 1, 2017
... is important to emphasize that all infected mice showed a powerful virus-specific immune response, indicating that the infection was effective, but did not lead to the development of clinical ...
Authors: Rustam N. Heydarov, Natalia F. Lomakina, Elizaveta Yu. Boravleva, Ivan S. Kholodilov, Alexandra S. Gambaryan, Vladimir M. Mikhailovich, Eugene E. Fesenko
Volume 4, Number 1, 2017
... [57]. The analysis of the clinical data shows that the immune response induced by both licensed vaccines is inconsistent. Thus, the pre-pandemic vaccine ...
Authors: Julia Romanova
Том 2, номер 1, 2015
... The system of genetic control of innate immune responses to influenza infection and gene function allows for the development of systemic treatment of influenza with a focus on the phenotype ...
Authors: О.И. Киселев, А.Б. Комиссаров, О.С. Коншина, М.Н. Дмитриева, Э.Г. Деева, Т.В. Сологуб, В.И. Покровский
Volume 2, Number 1, 2015
... Preparedness Plan measures and rapid response of National Healthcare Service. The last pandemic events were caused by the novel swine origin influenza A(H1N1)pdm09 virus that spread initially from Mexico ...
Authors: Anna A. Sominina, Maria M. Pisareva, Mikhail P. Grudinin, Mikhail Yu. Eropkin, Nadezhda I. Konovalova, Vera F. Sukhovetskaya, Olga I. Afanasieva, Lubov V. Voloshuk, Andrey B. Komissarov, Zhanna V. Buzitskaya, Artem V. Fadeev, Kirill A. Stolyarov, Elizaveta A. Smorodintseva, Veronika S. Afanasieva, Marina A. Yanina, Vitalii V. Gonchar, Ludmila V. Osidak, Alexey A. Go
Volume 3, Number 1, 2016
... 72 h the splenocytes of immune animals were hybridized with the mouse myeloma cells of the PxAg.653 line in 10 : 1 ratio in the presence of 50% PEG-2000 solution in DMEM. The traditional ...
Authors: Evgeniy V. Sorokin, Tatyana R. Tsareva, Anna A. Sominina, Maria M. Pisareva, Andrey B. Komissarov, Аnna А. Kosheleva
Volume 2, Number 1, 2015
... important issue. The most common method of identification of the newly isolated influenza viruses is the hemagglutination inhibition assay (HAI) with the use of specific immune animal sera. This ...
Authors: Vera Krivitskaya, Evgeniy Sorokin, Tatyana Tsareva, Ekaterina Petrova, Nadezhda Konovalova, Maria Pisareva, Zhanna Buzitskaya, Tatyana Smirnova, Anna Sominina
Volume 1, number 1, 2014
... applied [1]. For subvirion H5N1 vaccine, two doses of 45-90 µg was necessary to get an antibody response in more than half of the subjects according to ...
Authors: Mariia Sergeeva, Artem Krokhin, Mikhail Matrosovich, Tatyana Matrosovich, Markus Wolschek, Oleg Kiselev, Julia Romanova
Volume 2, Number 1, 2015
... considered as risk factors. On the other hand, the disorders of the central nervous system and immune system are the main factors leading to mortality from influenza among the children. It is important to ...
Authors: Ludmila S. Karpova, Nina M. Popovtseva, Tatyana P. Stolyarova, Nadezhda I. Konovalova, Mikhail Y. Eropkin, Elena I. Burtzeva, Elena L. Feodoritova, Anna A. Sominina
Volume 1, number 1, 2014
... experts in this field, thereby enabling scientists to identify the pathogen, to genotype it, and to develop reliable analytical test systems for virus identification. An inadequate or untimely response ...
Authors: Dr. J. Romanova, Editor-in-Chief