ISSN 2500-2236
DOI-prefix: 10.18527/2500-2236

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Volume 1, number 1, 2014
... H5N1 influenza vaccine quality is affected by hemagglutinin conformational stability ...
Authors: Mariia Sergeeva, Artem Krokhin, Mikhail Matrosovich, Tatyana Matrosovich, Markus Wolschek, Oleg Kiselev, Julia Romanova
Volume 4, Number 1, 2017
...   However, the pH of endosomes in both of these cell lines is higher than the pH essential for triggering a conformational change of the hemagglutinin (HA) of human influenza viruses, which ...
Authors: Julia Romanova
Volume 6, Number 1, 2019
... Comparative analysis of the influenza H3N2 viruses circulating in humans during 1968-2018 has shown high NSP variability, which was similar to that shown for the hemagglutinin (HA) and neuraminidase (NA ...
Authors: Oleg P. Zhirnov, Tatyana E. Konakova, Darisuren Anhlan, Stephan Ludwig, Elena I. Isaeva
Volume 3, Number 1, 2016
... In this study, we selected the escape mutants of influenza B/Florida/04/2006 strain (Yamagata-like lineage) using monoclonal antibodies (mAb) to hemagglutinin (HA). ...
Authors: Evgeniy V. Sorokin, Tatyana R. Tsareva, Anna A. Sominina, Maria M. Pisareva, Andrey B. Komissarov, Аnna А. Kosheleva
Том 4, номер 1, 2017
... PDZ domain; 3) the presence of stop codons and substitution N66S in the reading frame of the viral protein PB1-F2; 4) the presence of the polybasic site for hemagglutinin cleavage. ...
Authors: Р. Н. Гейдаров, Н. Ф. Ломакина, Е. Ю. Боравлева, И.С. Холодилов, А. С. Гамбарян, В. М. Михайлович, Е. Е. Фесенко
Volume 4, Number 1, 2017
... The microarray helps to determine 1) the hemagglutinin and neuraminidase proteins subtype; 2) the primary structure of the C-terminal sequence of the viral NS1 protein, which serves as a ligand for the ...
Authors: Rustam N. Heydarov, Natalia F. Lomakina, Elizaveta Yu. Boravleva, Ivan S. Kholodilov, Alexandra S. Gambaryan, Vladimir M. Mikhailovich, Eugene E. Fesenko
Volume 3, Number 1, 2016
... The genes coding for the hemagglutinin (HA) and the neuraminidase (NA) are inherited from the modern epidemic virus while the remaining six genes coding the non-glycosylated proteins – from the ...
Authors: Yulia A. Desheva, Tatiana A. Smolonogina, Galina O. Landgraf, Larisa G. Rudenko
Volume 2, Number 1, 2015
... The detection step of this method is an interaction of the subtype-specific monoclonal antibodies (mAbs) with the viral hemagglutinin (НА) molecule. ...
Authors: Vera Krivitskaya, Evgeniy Sorokin, Tatyana Tsareva, Ekaterina Petrova, Nadezhda Konovalova, Maria Pisareva, Zhanna Buzitskaya, Tatyana Smirnova, Anna Sominina
Volume 3, Number 1, 2016
... We report here that the hemagglutinin (HA) of A/Hong Kong/1035/1998 virus contained the mutation 10Ile→Val in the HA2 subunit, that increased the pH threshold of HA conformational change (pH of activation ...
Authors: Andrea Wolkerstorfer, Dietmar Katinger, Julia Romanova
Volume 6, Number 1, 2019
... Influenza A viruses in turn are divided into subtypes depending on the type of the main surface glycoproteins of the virus – hemagglutinin (HA) and neuraminidase (NA). ...
Authors: Svetlana V. Babii, Liudmyla V. Leibenko, Larysa V. Radchenko, Olga S. Golubka, Nataliia V. Teteriuk, Alla P. Mironenko
Том 2, номер 1, 2015
... The detection step of this method is an interaction of the subtype-specific monoclonal antibodies (mAbs) with the viral hemagglutinin (НА). ...
Authors: В.З. Кривицкая, Е.В. Сорокин, Т.Р. Царева, Е.Р. Петрова, Н.И. Коновалова, М.М. Писарева, Ж.В. Бузицкая, Т.Д. Смирнова, А.А. Соминина
Том 3, номер 1, 2016
... In this study, we selected the escape mutants of influenza B/Florida/04/2006 strain (Yamagata-like lineage) using monoclonal antibodies (mAb) to hemagglutinin (HA). ...
Authors: Е. В. Сорокин, Т. Р. Царева, А. А. Соминина, М. М. Писарева, А. Б. Комиссаров, А. А. Кошелева
Том 4, номер 1, 2017
...   However, the pH of endosomes in both of these cell lines is higher than the pH essential for triggering a conformational change of the hemagglutinin (HA) of human influenza viruses, which ...
Authors: Ю.Р. Романова
Том 6, номер 1, 2019
... Comparative analysis of the influenza H3N2 viruses circulating in humans during 1968-2018 has shown high NSP variability, which was similar to that shown for the hemagglutinin (HA) and neuraminidase (NA ...
Authors: О. П. Жирнов, Т. Е. Конакова, Д. Анхлан, С. Людвиг, Е. И. Исаева
Volume 2, Number 1, 2015
... Viruses containing specific substitutions T82K, Y94H, R145K, R208K, R225K in the hemagglutinin (HA) and V234M, D382N in neuraminidase (NA) formed genetically heterogeneous group of clade 2 viruses. ...
Authors: Mikhail P. Grudinin, Maria M. Pisareva, Andrey B. Komissarov, Anna A. Kosheleva, Zhanna V. Buzitskaya, Marina A. Stukova, Alexandra V. Prokopetz, Daria M. Danilenko, Nadezhda I. Konovalova, Tamara G. Lobova, Anna A. Sominina, Oleg I. Kiselev
Volume 3, Number 1, 2016
... The antigenic properties of influenza virus are determined by the surface glycoproteins - hemagglutinin (HA or H) and neuraminidase (NA or N). ...
Authors: Andrej Y. Egorov
Volume 5, Number 1, 2018
... This inactivated vaccine was based on reassortants engineered by reverse genetics, which contain the H5 hemagglutinin (HA) and N1 neuraminidase (NA) from H5N1 viruses and the remaining genes from A/Puerto ...
Authors: Elizaveta Boravleva, Alexandra Gambaryan
Volume 5, Number 1, 2018
... poses the greatest threat due to its circulation in different animal species and ability to reassort genomic fragments leading to the rapid modification of the main surface antigens of the virus – hemagglutinin ...
Authors: Andrej Egorov